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  Vol. 8 No. 2, March 1999 TABLE OF CONTENTS
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Biological, Social, and Behavioral Factors Associated With Premenstrual Syndrome

Patricia A. Deuster, PhD, MPH; Tilahun Adera, MPH, PhD; Jeannette South-Paul, MD

Arch Fam Med. 1999;8:122-128.

Objective  To investigate the influence of various biological, socioeconomic, and behavioral factors on premenstrual syndrome (PMS).

Design  Random-digit dialing technique. Of 7900 calls from all area codes, exchanges, and 2 digits known to be open in Virginia, with a pair of random digits, 1700 women were eligible for telephone interviews. A total of 874 women completed interviews, for a response rate of 67%.

Setting  State of Virginia.

Patients or Other Participants  All women between the ages of 18 and 44 years and living in Virginia between August 1 and September 15, 1994, were eligible.

Main Outcome Measures  Scores on Menstrual Distress Questionnaire, biological variables, lifestyle behaviors, socioeconomic status, and menstrual and reproductive history.

Results  Of the 874 women, 8.3% (95% confidence interval, 6.4%-10.2%) experienced PMS. Adjusted prevalence odds ratios for perceived stress and alcohol intake were 3.7 and 2.5, respectively, in women with PMS. Women with PMS were 2.9 times more likely to be physically active than women without PMS. Younger women, black women, and women with longer menses were more likely to have PMS.

Conclusions  Scores on the stress scale and alcohol intake support the concept that PMS is stress related; intervention strategies to cope with stress may be effective. Further study will be required to determine the influence of race on PMS and whether women with PMS exercise more regularly than women without PMS because they believe exercise is effective in attenuating their symptoms.


From the Departments of Military and Emergency Medicine (Dr Deuster) and Family Medicine (Dr South-Paul), Uniformed Services University of the Health Sciences, Bethesda, Md, and Department of Preventive Medicine and Community Health, Medical College of Virginia, Richmond (Dr Adera).


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