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Do Beta-Blockers Lead to Diabetes?
Arch Fam Med. 2000;9:547.
In a study following the development of atherosclerotic risk factors, diabetes developed within the next 6 years at a higher rate in patients with hypertension treated with beta-blockers than those treated with thiazide diuretics, angiotensin-converting-enzyme inhibitors, or calcium-channel blockers, or compared to patients without hypertension. The patients on beta-blockers had a 28% higher rate of the development of diabetes (relative hazard, 1.28; 95% confidence interval, 1.04-1.57). (N Engl J Med. 2000;342:905-912).
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