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The Emerging Role of Vitamins as Antioxidants
Larry E. Johnson, MD, PhD
Arch Fam Med. 1994;3(9):809-818.
References
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1. Subcommittee on the Tenth Edition of the RDAs, Food and Nutrition Board, Commission on Life Sciences, National Research Council. Recommended Dietary Allowances. 10th ed. Washington, DC: National Academy Press; 1989.
2. Weisburger JH. Nutritional approach to cancer prevention with emphasis on vitamins, antioxidants, and carotenoids. Am J Clin Nutr. 1991;53(suppl):226S-237S.
PUBMED
3. Southorn PA, Powis G. Free radicals in medicine, II: involvement in human disease. Mayo Clin Proc. 1988;63:390-408.
PUBMED
4. Stogner SW, Payne DK. Oxygen toxicity. Ann Pharmacother. 1992;26:1554-1562.
ABSTRACT
5. Rice-Evans CA, Diplock AT. Current status of antioxidant therapy. Free Radic Biol Med. 1993;15:77-96.
PUBMED
6. Bankson DD, Kestin M, Rifai N. Role of free radicals in cancer and atherosclerosis. Clin Lab Med. 1993;13:463-480.
PUBMED
7. Bulkley GB. Free radicals and other reactive oxygen metabolites: clinical relevance and the therapeutic efficacy of antioxidant therapy. Surgery. 1993;113:479-483.
PUBMED
8. Schiller HJ, Reilly PM, Bulkley GB. Antioxidant therapy. Crit Care Med. 1993;21(suppl):S92-S102.
PUBMED
9. Chow CK. Vitamin E and oxidative stress. Free Radic Biol Med. 1991;11:215-232.
PUBMED
10. Cutler RG. Antioxidants and aging. Am J Clin Nutr. 1991;53(suppl):373S-379S.
PUBMED
11. Sohol RS, Orr WC. Relationship between antioxidants, prooxidants, and the aging process. Ann N Y Acad Sci. 1992;663:74-84.
PUBMED
12. Ames BN, Shigenaga MK. Oxidants are a major contributor to aging. Ann N Y Acad Sci. 1992;663:85-96.
PUBMED
13. Barja de Quiroga G, Lopez-Torres M, PerezCampo R. Relationship between antioxidants, lipid peroxidation and aging. In: Emerit I, Chance B, eds. Free Radicals and Aging (EXS). Basel, Switzerland: Birkhauser; 1992:109-123. 14. Sohal RS. The free radical hypothesis of aging: an appraisal of the current status. Aging Clin Exp Res. 1993;5:3-17.
PUBMED
15. Marzatico F, Cafe C. Oxygen radicals and other toxic oxygen metabolites as key mediators of the central nervous system tissue injury. Funct Neurol. 1993;8:51-66.
PUBMED
16. Sastre J, Asensi M, Gasco E, et al. Exhaustive physical exercise causes oxidation of glutathione status in blood: prevention by antioxidant administration. Am J Physiol. 1992;263 (suppl):R992-R995.
PUBMED
17. Meydani M, Evans WJ, Handelman G, et al. Protective effect of vitamin E on exercise-induced oxidative damage in young and older adults. Am J Physiol. 1993;264(suppl):R992-R998.
PUBMED
18. Sies H. Strategies of antioxidant defense. Eur J Biochem. 1993;215:213-219.
PUBMED
19. Maxwell SRJ. Can anti-oxidants prevent ischaemic heart disease? J Clin Pharm Ther. 1993;18:85-95.
PUBMED
20. Niki E. Action of ascorbic acid as a scavenger of active and stable oxygen radicals. Am J Clin Nutr. 1991;54(suppl):1119S-1124S.
PUBMED
21. Sevanian A, Davies KJA, Hochstein P. Serum urate as an antioxidant for ascorbic acid. Am J Clin Nutr. 1991;54(suppl):1129S-1134S.
PUBMED
22. Yagi K, Komura S. Inhibitory effect of female hormones on lipid peroxidation. Biochem Int. 1986;13:1051-1055.
PUBMED
23. Mooradian AD. Antioxidant properties of steroids. J Steroid Biochem Mol Biol. 1993;45:509-511.
PUBMED
24. Ho CT, Chen Q, Shi H, et al. Antioxidative effect of polyphenol extract prepared from various Chinese teas. Prev Med. 1992;21:520-525.
PUBMED
25. Santiago LA, Hiramatsu M, Mori A. Japanese soybean paste miso scavenges free radicals and inhibits lipid peroxidation. J Nutr Sci Vitaminol. 1992;38:279-304.
26. Phelps S, Harris WS. Garlic supplementation and lipoprotein oxidation susceptibility. Lipids. 1993;28:475-477.
PUBMED
27. Luc G, Fruchart JC. Oxidation of lipoproteins and atherosclerosis. Am J Clin Nutr. 1991;53:(suppl):206S-209S.
PUBMED
28. Steinberg D. Antioxidants in the prevention of human atherosclerosis. Circulation. 1992;85:2338-2344.
29. Grundy SM. Overview. Clin Cardiol. 1993;16 (suppl_1):I1-I2.
PUBMED
30. Jialal I, Grundy SM. Influence of antioxidant vitamins on LDL oxidation. Ann N Y Acad Sci. 1992;669:237-248.
PUBMED
31. Schwartz CJ, Valente AJ, Sprague EA. A modern view of atherogenesis. Am J Cardiol. 1993;71(suppl):9B-14B.
PUBMED
32. Lyons TJ. Glycation and oxidation: a role in the pathogenesis of atherosclerosis. Am J Cardiol. 1993;71(suppl):26B-31B.
PUBMED
33. Grundy SM. Oxidized LDL and atherogenesis: relation to risk factors for coronary heart disease. Clin Cardiol. 1993;16(suppl 1):I3-I5.
PUBMED
34. Janero DR. Therapeutic potential of vitamin E in the pathogenesis of spontaneous atherogenesis. Free Radic Biol Med. 1991;11:129-144.
PUBMED
35. Regnstrom J, Nilsson J, Tornvall P, et al. Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man. Lancet. 1992;339:1183-1186.
PUBMED
36. Kuzuya M, Kuzuya F. Probucol as an antioxidant and antiatherogenic drug. Free Radic Biol Med. 1993;14:67-77.
PUBMED
37. Steinberg D. Antioxidant vitamins and coronary heart disease. N Engl J Med. 1993;328:1487-1489.
PUBMED
38. Esterbauer H, Dieber-Rotheneder M, Striegl G, et al. Role of vitamin E in preventing the oxidation of low-density lipoprotein. Am J Clin Nutr. 1991;53(suppl):314S-321S.
PUBMED
39. Frei B. Ascorbic acid protects lipids in human plasma and low-density lipoprotein against oxidative damage. Am J Clin Nutr. 1991;54(suppl):1113S-1118S.
PUBMED
40. Retsky KL, Freeman MW, Frei B. Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. J Biol Chem. 1993;268:1304-1309.
FREE FULL TEXT
41. Reaven PD, Khouw A, Beltz WF, et al. Effect of dietary antioxidant combinations in humans: protection of LDL by vitamin E but not by beta-carotene. Arterioscler Thromb. 1993;13:590-600.
FREE FULL TEXT
42. Bowry VW, Ingold KU, Stocker R. Vitamin E in human low-density lipoprotein: when and how this antioxidant becomes a pro-oxidant. Bio-chem J. 1992;288:341-344.
PUBMED
43. Jialal I, Fuller CJ. Oxidized LDL and antioxidants. Clin Cardiol. 1993;16(suppl 1):16-19.
PUBMED
44. Johnston CS, Meyer CG, Srilakshmi JC. Vitamin C elevates red blood cell glutathione in healthy adults. Am J Clin Nutr. 1993;58:103-105.
FREE FULL TEXT
45. Gey KF, Moser UK, Jordan P, et al. Increased risk of cardiovascular disease at suboptimal plasma concentrations of essential antioxidants: an epidemiological update with special attention to carotene and vitamin C. Am J Clin Nutr. 1993;57(suppl):787S-797S.
PUBMED
46. Hennekens CH, Gaziano JM. Antioxidants and heart disease: epidemiology and clinical evidence. Clin Cardiol. 1993;16(suppl I):I10-I15.
PUBMED
47. Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiology. 1992;3:194-202.
PUBMED
48. Eichholzer M, Stahelin HB, Gey KF. Inverse cor-relation between essential antioxidants in plasma and subsequent risk to develop cancer, ischemic heart disease and stroke respectively: 12-year follow-up of the Prospective Basel Study. In: Emerit I, Chance B, eds. Free Radicals and Aging (EXS). Basel, Switzerland: Birkhauser; 1992:398-410. 49. Stampfer MJ, Hennekens CH, Manson JE, et al. Vitamin E consumption and the risk of coronary disease in women. N Engl J Med. 1993;328:1444-1449.
PUBMED
50. Rimm EB, Stampfer MJ, Ascherio A, et al. Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med. 1993;328:1450-1456.
PUBMED
51. Gaziano JM, Manson JE, Ridker PM, et al. Beta carotene therapy for chronic stable angina. Circulation. 1991;82(suppl III):201.
52. Gerster H. Potential role of beta-carotene in the prevention of cardiovascular disease. Int J Vitam Nutr Res. 1991;61:277-291.
PUBMED
53. Gutteridge JMC, Quinlan GJ. Antioxidant protection against organic and inorganic radicals by normal human plasma: the important primary role for iron-binding and iron-oxidizing proteins. Biochim Biophys Acta. 1993;1156:144-150.
PUBMED
54. Salonen JT, Nyyssonen K, Korpela H, et al. High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men. Circulation. 1992;86:803-811.
FREE FULL TEXT
55. Ascherio A, Willett WC, Rimm EB, et al. Dietary iron intake and risk of coronary disease among men. Circulation. 1994;89:969-974.
FREE FULL TEXT
56. Ascherio A, Willett WC. Are body iron stores related to the risk of coronary heart disease? N Engl J Med. 1994;330:1152-1154.
PUBMED
57. Sullivan JL. Iron and the sex difference in heart disease risk. Lancet. 1981;1:1293-1294.
PUBMED
58. Bunce GE, Kinoshita J, Horwitz J. Nutritional factors in cataract. Annu Rev Nutr. 1990;10:233-254.
PUBMED
59. Robertson J, Donner AP, Trevithick JR. Vitamin E intake and risk of cataracts in humans. Ann N Y Acad Sci. 1989;570:372-382.
PUBMED
60. Varma SD. Scientific basis for medical therapy of cataracts by antioxidants. Am J Clin Nutr. 1991;53(suppl):335S-345S.
PUBMED
61. Taylor A. Role of nutrients in delaying cataracts. Ann N Y Acad Sci. 1992;669:111-124.
PUBMED
62. Taylor A. Cataract: relationships between nutrition and oxidation. J Am Coll Nutr. 1993;12:138-146.
ABSTRACT
63. Garland DL. Ascorbic acid and the eye. Am J Clin Nutr. 1991;54(suppl):1198S-1202S.
PUBMED
64. Robertson JMD, Donner AP, Trevithick JR. A possible role for vitamins C and E in cataract prevention. Am J Clin Nutr. 1991;53(suppl):346S-351S.
PUBMED
65. Jacques PF, Chylack LT Jr. Epidemiologic evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention. Am J Clin Nutr. 1991;53(suppl):352S-355S.
PUBMED
66. Knekt P, Heliovaara M, Rissanen A, et al. Se. rum antioxidant vitamins and risk of cataract. BMJ. 1992;305:1392-1394.
FREE FULL TEXT
67. Hankinson SE, Stampfer MJ, Seddon JM, et al. Nutrient intake and cataract extraction in women: a prospective study. BMJ. 1992;305:335-339.
FREE FULL TEXT
68. Leske MC, Chylack LT, Wu S-Y, The Lens Opacities Case-Control Study Group. The Lens Opacities Case-Control Study: risk factors for cataract. Arch Ophthalmol. 1991;109:244-251.
FREE FULL TEXT
69. Seddon JM, Christen WG, Manson JE, et al. The use of vitamin supplements and the risk of cataract among US male physicians. Am J Public Health. 1994;84:788-792.
PUBMED
70. Eye Disease Case-Control Study Group. Antioxidant status and neovascular age-related macular degeneration. Arch Ophthalmol. 1993;111:104-109.
FREE FULL TEXT
71. Prashar S, Pandav SS, Gupta A, et al. Antioxidant enzymes in RBCs as a biological index of age related macular degeneration. Acta Ophthalmol. 1993;71:214-218.
PUBMED
72. Schwartz JL, Antoniades DZ, Zhao S. Molecular and biochemical reprogramming of oncogenesis through the activity of prooxidants and antioxidants. Ann N Y Acad Sci. 1993;686:262-279.
PUBMED
73. Block G. Vitamin C and cancer prevention: the epidemiologic evidence. Am J Clin Nutr. 1991;53(suppl):270S-282S.
PUBMED
74. Block G. The data support a role for antioxidants in reducing cancer risks. Nutr Rev. 1992;50:207-213.
PUBMED
75. Ziegler RG. Vegetables, fruits, and carotenoids and the risk of cancer. Am J Clin Nutr. 1991;53(suppl):251S-259S.
PUBMED
76. Ausman LM. Fiber and colon cancer: does the current evidence justify a preventive policy? Nutr Rev. 1993;51:57-63.
PUBMED
77. Freeland-Graves JH, Greninger SA, Graves GR, et al. Health practices, attitudes, and beliefs of vegetarians and nonvegetarians. J Am Diet Assoc. 1986;86:913-918.
PUBMED
78. Krinsky NI. Effects of carotenoids in cellular and animal systems. Am J Clin Nutr. 1991;53(suppl):238S-246S.
PUBMED
79. Comstock GW, Helzlsouer KJ, Bush TL. Prediagnostic serum levels of carotenoids and vitamin E as related to subsequent cancer in Washington County, Maryland. Am J Clin Nutr. 1991;53(suppl):260S-264S.
PUBMED
80. Stahelin HB, Gey KF, Eichholzer M, et al. Batacarotene and cancer prevention: the Basel study. Am J Clin Nutr. 1991;53(suppl):265S-269S.
PUBMED
81. Stich, HF, Babu M, Sankaranarayanan R, et al. Remission of precancerous lesions in the oral cavity of tobacco chewers and maintenance of the protective effect of beta-carotene or vitamin A. Am J Clin Nutr. 1991;53(suppl):298S-304S.
PUBMED
82. Marubini E, Decarli A, Costa A, et al. The relationship of dietary intake and serum levels of retinol and beta-carotene with breast cancer. Cancer. 1988;61:173-180.
PUBMED
83. Potischman N, McCulloch CE, Byers T, et al. Breast cancer and dietary and plasma concentration of carotenoids and vitamin A. Am J Clin Nutr. 1990;52:909-915.
FREE FULL TEXT
84. Van Poppel G. Carotenoids and cancer: an up-date with emphasis on human intervention studies. Eur J Cancer. 1993;29A:1335-1344.
85. Hunter DJ, Manson JE, Colditz GA, et al. A prospective study of the intake of vitamins C, E, and A and the risk of breast cancer. N Engl J Med. 1993;329:234-240.
PUBMED
86. Howe GR, Hirohata T, Hislop G, et al. Dietary factors and risk of breast cancer: combined analysis of 12 case-control studies. J Natl Cancer Inst. 1990;82:561-569.
FREE FULL TEXT
87. Blot WJ, Li JY, Taylor PR, et al. Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. J Natl Cancer Inst. 1993;85:1483-1492.
FREE FULL TEXT
88. Biasco G, Paganelli GM, Brandi G, et al. Chemoprevention of colorectal cancer: role of antioxidant vitamins. Eur Cancer Prev. 1992;1 (suppl 3):87-91.
89. Roncucci L, Donato PD, Carati L, et al. Antioxidant vitamins or lactulose for the prevention of the recurrence of colorectal adenomas. Dis Colon Rectum. 1993;36:227-234.
PUBMED
90. Knekt P, Aromaa A, Maatela J, et al. Vitamin E and cancer prevention. Am J Clin Nutr. 1991;53(suppl):283S-286S.
PUBMED
91. Knekt P. Vitamin E and cancer: epidemiology. Ann N Y Acad Sci. 1992;669:269-279.
PUBMED
92. Knekt P. Vitamin E and smoking and the risk of lung cancer. Ann N Y Acad Sci. 1993;686:280-288.
PUBMED
93. Mayne ST, Janerich DT, Greenwald P, et al. Dietary beta carotene and lung cancer risk in US nonsmokers. J Natl Cancer Inst. 1994;86:33-38.
FREE FULL TEXT
94. Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994;330:1029-1035.
PUBMED
95. Simmons K. Evaluating vitamin prophylaxis for cancer. JAMA. 1986;255:1832-1835.
FREE FULL TEXT
96. Malone WF. Studies evaluating antioxidants and beta-carotene as chemopreventives. Am J Clin Nutr. 1991;53(suppl):305S-313S.
PUBMED
97. Veronesi U, De Palo G, Costa A, et al. Chemoprevention of breast cancer with retinoids. J Natl Cancer Inst Monogr. 1992;12:93-97.
98. Birt DF. Update on the effects of vitamins A, C, and E and selenium on carcinogenesis. Proc Soc Exp Biol Med. 1986;183:311-320.
FREE FULL TEXT
99. Pastorino U, Chiesa G, Infante M, et al. Safety of high-dose vitamin A: randomized trial on lung cancer chemoprevention. Oncology. 1991;48:131-137.
PUBMED
100. Korner WF, Vollm J. New aspects of the tolerance of retinol in humans. Int J Vitam Nutr Res. 1975;45:363-372.
PUBMED
101. Bendich A, Langseth L. Safety of vitamin A. Am J Clin Nutr. 1989;49:358-371.
FREE FULL TEXT
102. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr. 1990;52:183-202.
FREE FULL TEXT
103. Bendich A, Machlin LJ. Safety of oral intake of vitamin E. Am J Clin Nutr. 1988;48:612-619.
FREE FULL TEXT
104. Reaven PD, Witztum JL. Comparison of supplementation of RRR-alpha-tocopherol and racemic alpha-tocopherol in humans. Arterioscler Thromb. 1993;13:601-608.
FREE FULL TEXT
105. Mitchel REJ, McCann R. Vitamin E is a complete tumor promoter in mouse skin. Carcinogenesis. 1993;14:659-662.
FREE FULL TEXT
106. Rivers JM. Safety of high-level vitamin C ingestion. Ann N Y Acad Sci. 1987;498:445-454.
PUBMED
107. Jacob RA, Otradovec CL, Russell RM, et al. Vitamin C status and nutrient interactions in a healthy elderly population. Am J Clin Nutr. 1988;48:1436-1442.
FREE FULL TEXT
108. Omaye ST, Skala JH, Jacob RA. Rebound effect with ascorbic acid in adult males. Am J Clin Nutr. 1988;48:379-380.
FREE FULL TEXT
109. Block G, Dresser CM, Hartman AM, et al. Nutrient sources in the American diet: quantitative data from the NHANES II survey, I: vitamins and minerals. Am J Epidemiol. 1985;122:13-26.
FREE FULL TEXT
110. Porrini N, Simonetti P, Ciappellano S, et al. Vitamin A, E and C nutriture of elderly people in north Italy. Int J Vitam Nutr Res. 1987;57:349-355.
PUBMED
111. Panemangalore M, Lee CJ. Evaluation of the indices of retinol and alpha-tocopherol status in free-living elderly. J Gerontol. 1992;47:B98-B104.
ABSTRACT
112. Sklan D. Vitamin A in human nutrition. Prog Food Nutr Sci. 1987;11:39-55.
PUBMED
113. Olson JA. Recommended dietary intakes (RDI) of vitamin A in humans. Am J Clin Nutr. 1987;45:704-716.
FREE FULL TEXT
114. Russell RM, Suter PM. Vitamin requirements of elderly people: an update. Am J Clin Nutr. 1993;58:4-14.
FREE FULL TEXT
115. Blomhoff R, Green MH, Berg T, et al. Transport and storage of vitamin A. Science. 1990;250:399-404.
FREE FULL TEXT
116. Ohrvall M, Tengblad S, Vessby B. Lower tocopherol serum levels in subjects with abdominal adiposity. J Intern Med. 1993;234:53-60.
PUBMED
117. Colditz GA, Branch LG, Lipnick RJ, et al. In-creased green and yellow vegetable intake and lowered cancer deaths in an elderly population. Am J Clin Nutr. 1985;41:32-36.
FREE FULL TEXT
118. Micozzi MS, Brown ED, Taylor PR, et al. Carotenodermia in men with elevated carotenoid intake from foods and beta-carotene supplements. Am J Clin Nutr. 1988;48:1061-1064.
FREE FULL TEXT
119. Olson JA, Hodges RE. Recommended dietary intakes (RDI) of vitamin C in humans. Am J Clin Nutr. 1987;45:693-703.
FREE FULL TEXT
120. Gerster H. Human vitamin C requirements. Z Ernahrungswiss. 1987;26:125-137.
PUBMED
121. McClean HE, Dodds PM, Stewart AW, et al. Nutrition of elderly men living alone, II: vitamin C and thiamine status. N Z Med J. 1976;84:345-348.
PUBMED
122. Morgan DR. A case of bachelor scurvy. Practitioner. 1987;231:450-455.
PUBMED
123. Mandal SK, Ray AK. Vitamin C status of elderly patients on admission into an assessment geriatric ward. J Int Med Res. 1987;15:96-98.
PUBMED
124. Garry PJ, Vanderjagt DJ, Hunt WC. Ascorbic acid intakes and plasma levels in healthy elderly. Ann N Y Acad Sci. 1987;498:90-99.
PUBMED
125. Blanchard J, Conrad KA, Mead RA, et al. Vitamin C disposition in young and elderly men. Am J Clin Nutr. 1990;51:837-845.
FREE FULL TEXT
126. Machlin LJ. Vitamin E. In: Machlin LJ, ed. Hand-book of Vitamins. 2nd ed. New York, NY: Marcel Dekker Inc; 1991:99-144. 127. Ferns, GAA, Konneh M, Anggard EE. Vitamin E: the evidence for an anti-atherogenic role. Artery. 1993;20:61-94.
PUBMED
128. Steiner M. Vitamin E: more than an antioxidant. Clin Cardiol. 1993;16(suppl I):I16-I18.
PUBMED
129. Meydani SN, Barklund MP, Liu S, et al. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects. Am J Clin Nutr. 1990;52:557-563.
FREE FULL TEXT
130. Simonoff M, Sergeant C, Garnier N, et al. Antioxidant status (selenium, vitamins A and E) and aging. In: Emerit I, Chance B, eds. Free Radicals and Aging (EXS). Basel, Switzerland: Birkhauser; 1992:368-397. 131. Machlin LJ. Clinical uses of vitamin E. Acta Vitaminol Enzymol. 1985;7(suppl):33-43.
PUBMED
132. Morrow MJ. Neurologic complications of vitamin E deficiency: case report and review of the literature. Bull Clin Neurosci. 1985;50:53-60.
PUBMED
133. Block G. Dietary guidelines and the results of food consumption surveys. Am J Clin Nutr. 1991;53(suppl):356S-357S.
PUBMED
134. Bieri JG. Are the recommended allowances for dietary antioxidants adequate? Free Radic Biol Med. 1987;3:193-197.
PUBMED
135. Diplock AT. Dietary supplementation with antioxidants: is there a case for exceeding the recommended dietary allowance? Free Radic Biol Med. 1987;3:199-201.
PUBMED
136. Draper HH, Bird RP. Micronutrients and cancer prevention: are the RDAs adequate? Free Radic Biol Med. 1987;3:203-207.
PUBMED
137. Voelker R. Radical approaches: is widespread testing and treatment for oxidative injuries coming soon? JAMA. 1993;270:2024.
FREE FULL TEXT
138. Wynder EL. Cancer prevention: optimizing life-styles with special reference to nutritional carcinogenesis. J Natl Cancer Inst Monogr. 1992;12:87-91.
139. Willett WC, Ascherio A. Trans fatty acids: are the effects only marginal? Am J Public Health. 1994;84:722-724.
PUBMED
140. Block G. Micronutrients and cancer: time for action? J Natl Cancer Inst. 1993;85:846-848.
FREE FULL TEXT
141. Vatassery GT. Vitamin E: neurochemistry and implications for neurodegeneration in Parkinson's disease. Ann N Y Acad Sci. 1992;669:97-110.
PUBMED
142. Olanow CW. An introduction to the free radical hypothesis in Parkinson's disease. Ann Neurol. 1992;32(suppl):S2-S9.
PUBMED
143. Calne DB. The free radical hypothesis in idiopathic Parkinsonism: evidence against it. Ann Neurol. 1992;32:799-803.
PUBMED
144. Fahn S, Cohen G. The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol. 1992;32:804-812.
PUBMED
145. The Parkinson Study Group. Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med. 1993;328:176-183.
PUBMED
146. Rosen DR, Siddique T, Patterson D, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 1993;326:59-62.
147. Adler LA, Peselow E, Rotrosen J, et al. Vitamin E treatment of tardive dyskinesia. Am J Psychiatry. 1993;150:1405-1407.
PUBMED
148. Hall ED. Lipid antioxidants in acute central nervous system injury. Ann Emerg Med. 1993;22:1022-1027.
PUBMED
149. Floyd RA, Carney JM. Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress. Ann Neurol. 1992;32(suppl):S22-S27.
PUBMED
150. Ferrari R, Ceconi C, Curello S, et al. Role of oxygen free radicals in ischemic and reperfused myocardium. Am J Clin Nutr. 1991;53 (suppl):215S-222S.
PUBMED
151. Kukreja RC, Hess ML. The oxygen free radical system: from equations through membraneprotein interactions to cardiovascular injury and protection. Cardiovasc Res. 1992;26:641-655.
FREE FULL TEXT
152. Korthuis RJ, Granger DN. Reactive oxygen metabolites, neutrophils, and the pathogenesis of ischemic-tissue/reperfusion. Clin Cardiol. 1993;16(suppl I):I19-I26.
PUBMED
153. Wechsler AS, Abd-Elfattah A. Future cardioprotective considerations. J Card Surg. 1993;8:492-502.
PUBMED
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