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Should Carisoprodol Be a Controlled Substance?
William M. Chop, Jr, MD
McLennan County Medical Education and Research Foundation Waco, Tex
Arch Fam Med. 1993;2(9):911.
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The "Brief Report" by Rust et al1 is important, and should encourage family physicians nationwide to be especially careful in prescribing carisoprodol. Carisoprodol abuse has concerned me since the mid-1980s when two patients at my semi-rural Oklahoma practice exhibited clear-cut drug-seeking behavior for carisoprodol. These patients regularly sought large quantities of carisoprodol, claimed that they had lost prescriptions, instigated calls and visits from friends and relatives specifically seeking the drug, and demonstrated other drug-seeking behaviors that I would usually associate with narcotics. Each patient displayed little objective evidence of the need for this drug, especially on a continuing basis. When, via a brief literature search, I learned about the abuse-prone active metabolite, meprobamate, and the sporadic case reports of abuse and dependence, I became suspicious about what was going on with my patients.
Over the next few years, I continued to come across carisoprodol-seeking patients in private practice and
. . . [Full Text PDF of this Article]
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