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Tissue Engineering of Small-Diameter Vascular Grafts

Hannover Medical School

Axel Haverich

Hannover Medical School

Small-diameter vascular grafts currently in use have limitations, including restricted availability, requirements for anticoagulant therapy under specific circumstances, neointimal hyperplasia, and aneurysm formation. This review provides an overview of the history and recent studies in the field of small-diameter vascular grafts, including arterial and venous autografts, allografts, xenografts, alloplastic prostheses, and tissue-engineering approaches.

Key Words: artery • cell seeding • endothelial cells • polytetrafluoroethylene • prosthesis • smooth muscle cells • tissue engineering • vascular graft

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