Table of Contents

December 2001; 1 (5)

Speaking of Pharmacology




  • Anesthesiology has been a subdiscipline of pharmacology for over a century. Still, the molecular mechanisms for induced unconsciousness remain open to debate.

  • A variety of lesser-known mammalian DNA polymerases function to prevent the shutdown of DNA replication. Can enzymes that "catalyze" mutation be targeted to prevent cancer?

  • GPCRs remain the most pharmaceutically targeted cell membrane receptors. Accessory proteins that promote GPCR functionality and transport to the cell surface suggest that half the fun, indeed, may be in getting there.

Beyond the Bench