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Small Interfering RNAs: A Revolutionary Tool for the Analysis of Gene Function and Gene Therapy
Table 1.
siRNA-Mediated Silencing in Cell Lines
| Cell line | Tissue origin | Reference |
|---|---|---|
| A-431 | human epidermoid carcinoma | (23) |
| A549 | human lung carcinoma | (72) |
| BV173 | human B-precursor leukemia | (77) |
| C-33A | human papilloma virus negative cervical carcinoma | (46) |
| CA46 | human Burkitt’s lymphoma | (77) |
| Caco2 | human colon epithelial cells | (61) |
| CHO | Chinese hamster ovary | (23) |
| COS-7 | African green monkey kidney | (9) |
| F5 | rat fibroblast | (32) |
| H1299 | human nonsmall cell lung carcinoma | (46) |
| HaCaT | human keratinocyte cell | (12) |
| HEK 293 | human embryonic kidney | (9) |
| HeLa | human papilloma virus positive cervical carcinoma | (9) |
| Hep3B | human hepatocellular carcinoma | (64) |
| HUVEC | human umbilical vein endothelial cells | (54) |
| IMR-90 | human diploid fibroblast | (41) |
| K562 | human chronic myelogenous leukemia, blast crisis | (77) |
| Karpas 299 | human T-cell lymphoma | (77) |
| MCF-7 | human breast cancer | (84) |
| MDA-MB-468 | human breast cancer | (84) |
| MV-411 | human acute monocytic leukemia | (77) |
| NIH/3T3 | mouse fibroblast | (9) |
| P19 | mouse embryonic carcinoma | (42) |
| SD1 | human acute lymphoblastic leukemia | (77) |
| SKBR3 | human breast cancer | (23) |
| U2OS | human osteogenic sarcoma cell | (59) |
