The TASK Family: Two-Pore Domain Background K+ Channels

Expression of TASK-1 and TASK-3 channels in mouse brain. Horizontal (upper) and sagittal (middle) sections of mouse brain were hybridized with [³³P]-labeled cRNA antisense probes complementary to TASK-1 (left) and TASK-3 (right). As a control, sagittal sections were hybridized to the corresponding [³³P]-labeled sense probes (lower). Note the differential distributions of TASK-1 and TASK-3 transcripts that also include some regions where channel expression is overlapping (arrowhead) (e.g., cerebellum and facial motoneurons).