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The Biology of Caveolae: Lessons from Caveolin Knockout Mice and Implications for Human Disease
Figure 1.
The caveolin gene family. A. The exon arrangement in Cav-1, Cav-2, and Cav-3 is indicated by boxes; the number of nucleotides in each exon is shown. B. The three caveolin proteins (Cav-1, Cav-2, and Cav-3), including the two isoforms of Cav-1, can be depicted in terms of N-terminal, transmembrane (TM), and C-terminal domains. The position of the conserved FEDVIAEP signature motif is illustrated.
