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Roadmap or Roadkill: A Pharmacologist’s Analysis of the NIH Molecular Libraries Initiative
Figure 1.
Anticipated operations flow chart of the Molecular Libraries Screening Centers Network. Compounds are provided by the NIH Small Molecule Repository. Assays are assigned to individual MLSCN Centers by the MLSCN Steering Committee after peer-review. High-throughput assays are conducted and the data are rapidly deposited in PubChem. Reiterative interactions among Network components will support the development and refinement of biological activities through the synthesis of new compounds and secondary assays.
