Figure 4: Photomicrographs of the frontal cortex. (a). Control Group indicating no histopathological changes. (b) 25 mg/kg caffeine group showing increase in cell density in the frontal cortex. (c) 30 mg/kg caffeine group showing increase in cell density in the frontal cortex. (d) 40 mg/kg caffeine group showing increase in cell density in the frontal cortex. (e) 60 mg/kg caffeine showing increase in cell density in the frontal cortex (H and E, ×100). M = Marginal zone; CP = Cortical plate; SP = Subcortical plate; IP = Intermediate plate; SVZ = Subventricular zone; VZ = Ventricular zone