- Institution: Stanford Univ Med Ctr Lane Med Lib/Periodical Dept/Rm L109
- Sign In as Member / Individual
Pharmacology of Store-operated Calcium Channels
Figure 4
Biphasic effect of 2-APB on Icrac.A) During thapsigargin-(TG)-activated store-operated Ca2+ entry in HEK293 cells, addition of 3 or 10 μM 2-APB enhances entry, whereas addition of 30 or 50 μM inhibits. B) Icrac in HEK293 cells overexpressing Orai1 and STIM1 is augmented by 20 μM 2-APB but inhibited by 50 μM. Adapted from (48).
