- Institution: Stanford Univ Med Ctr Lane Med Lib/Periodical Dept/Rm L109
- Sign In as Member / Individual
ROLE of MITOCHONDRIA in TOXIC OXIDATIVE STRESS
Figure 5.
Cytochromecis released from mitochondria by a two-step mechanism. Pore formation by Bax is required, but not sufficient for release of the hemoprotein from the mitochondria. Cytochrome c must first be detached from its binding to cardiolipin in the IMM to be released into the cytosol through the pores in the outer membrane.
