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Discovery and Therapeutic Promise of Selective Androgen Receptor Modulators
Figure 3.
Tissue-selective pharmacologic activity of S-4. A. Male rats were castrated and treated for 14 consecutive days with S-4. S-4 potently stimulates muscle growth, but is unable to maintain prostate size. Adapted from J. Pharmacol. Exp. Therap.304,1334 (2005). B. Testosterone stimulates muscle and prostate growth to the same extent.
