HETEROCYCLES

■ Selective Halogenation of 4-Oxo-4,5,6,7-tetrahydroindoles to 5-Halo-4,5,6,7-tetrahydeoindoles with Copper(II) Halides

Masakatsu Matsumoto,* Yasuko Ishoda, and Nobuko Watanabe

*Sagami Central Research Center, 4-4-1 Nishi-Ohnuma, Sagamihara, Kanagawa 229-0012, Japan

Abstract

Halogenation of 4-oxo-4,5,6,7-tetrahydroindoles with copper(II) bromide or copper(II) chloride gave selectively 5-halo-4-oxo-4,5,6,7-tetrahydroindoles, which were easily transformed to 4-hydroxyindoles by the action of lithium halide/lithium carbonate in dimethylformamide.

■ The Reaction of Enones with N-Subatituted Hydrazines and N-Substituted Ureas

Choji Kashima* and Nobutoshi Yoshiwara

*Department of Chemistry, University of Tsukuba, 1-1-1 Ten-nodai, Tsukuba-shi, Ibaraki, 305-8571, Japan

■ Oxidation of Indoles with Molybdenumperoxo Complex, MoO₅·HMPA

Tomomi Kawasaki, Chun-Sheng Chien, Takako Suzuki, Toshikatsu Takanami, and Masanori Sakamoto

*Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan

■ Pericyclic Reactions of Pyridine N-Oxides

Takuzo Hisano, Kazunobu Harano, Toshikazu Matsuoka, Ryuichi Fukuoka, Motoji Murase, and Hirotoshi Yamada

*Faculty of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-hon-machi, Kumamoto 862-0973, Japan

■ Selective Reactions of Active Methyl Groups on Pyridine and Quinoline Rings

Hiroshi Yamanaka, Takao Sakamoto, Hiroshi Yoshizawa, and Sumiko Nishimura

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

■ Reactions of Quinoline N-Oxides and Nitrobenzenes with Methylquinoline and -Pyridine Derivatives in the Presence of t-BuOK

Genji Iwasaki, Seitaro Saeki, Kazuko Wada, and Masatomo Hamana

*Faculty of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

■ Neighboring Group Participation by Pyridine Rings and N-Oxides. Synthesis and Reactions of 5,8-Dihydro-5,8-methanoisoquinoline Derivatives

Tadashi Irie, Yoko Hayashi, and Hiroshi Tanida

*Shionogi Research Laboratories, Shionogi & Co. Ltd., Fukushima-ku, Osaka 553-0002, Japan

■ A Convenient Preparation of Bipyridine Derivatives

Tsutomu Kawai, Naomichi Furukawa, and Shigeru Oae

*Department of Chemistry, University of Tsukuba, 1-1-1 Ten-nodai, Tsukuba-shi, Ibaraki, 305-8571, Japan

■ A New Method for α-Substitution in Nitrogen-containing Heterocycles

Norihiro Tokitoh, Renji Okazaki, and Naoki Inamoto

*Department of Chemistry, School of Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

■ Synthesis of β-Lactams Using the Photochemical Reaction of 4-Oxygenated 2-Pyridone Derivatives

Nobuya Katagiro, Masayuki Sato, Makoto Muto, Toshiyuki Sakamoto, Satoshi Saikawa, Chikara Kaneko, Toshihiko Naito, and Akemi Saito

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

■ Synthesis and Properties of Cyclophane Containing Hetero Aromatic. II. 13-Substituted [2.2]Metacyclo(3,5)pyridinophanes

Toshihide Kawashima, Yasuo Tohda, Masahiro Ariga, Yutaka Mori, and Shoichi Misumi

*Department of Chemistry, Faculty of Science, Osaka City University, Sugimoto, Sumiyoshi-ku, Osaka 558-8585, Japan

■ Synthesis of the Host Molecule Having Crown Ether and Cyclophane Units

Masayuki Takada, Masataka Kubo, Akira Youda, Kazuhiko Saigo, and Masaki Hasegawa

*Department of Synthetic Chemistry, Faculty of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

■ Synthesis of Fluorine Containing Pyrroles and Their Derivatives

Hiroo Toi, Michihide Homma, Hiroyuki Onda, Katsuhiro Aoyagi, Yasuhiro Aoyama, and Hisanobu Ogoshi

*Department of Material Science, Technological University of Nagaoka, Kamitomioka, Nagaoka, Niigata 949-54, Japan

■ Basicity and Redox-character of Pyrrole[3,2-b]pyrrole and Its Related Compounds

Tsutomu Kumagai, Shoji Tanaka, Kyosuke Satake, and Toshio Mukai

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

■ Reaction of Pyridinium or Isoquinolinium Ketene Dithioacetals with Aromatic N-Imines or S-Imines

Yoshinori Tominaga, Takeharu Michioka, Yukio Oniyama, Hiroto Goto, Yoshiro Matsuda, and Goro Kobayashi (deceased)

*Faculty of Pharmaceutical Sciences, Nagasaki University, 1-14, Bunkyo-machi, Nagasaki 852-8521, Japan

■ Reissert Type’s Reaction by Use of Phosphite (II)

Isao Takeuchi, Yasuhiro Shibata, and Yoshiki Hamada

*Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tenpaku, Nagoya 468-8503, Japan

■ Synthesis of 2-Substituted Dihydropyrimidines and Their Properties

Choji Kashima, Masao Shimizu, and Yoshimori Omote

*Department of Chemistry, University of Tsukuba, 1-1-1 Ten-nodai, Tsukuba-shi, Ibaraki, 305-8571, Japan

■ Introduction of C-Group into the Pyrazine Ring with Organoaluminium Compounds

Akihiro Ohta, Akira Inoue, Masakatsu Ohta, Tokuhiro Watanabe, and Yasuo Akita

*Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

■ Cyclic Peroxides. 11. Chemiluminescent Reaction Mechanism of N-Methyl-9-(dicarboalkoxymethyl)acridanes

Nobutaka Suzuki, Mitsumasa Nakaminami, Toshio Tsukamoto, Kathuhiko Iwasaki, and Yasuji Izawa

*Faculty of Engineering, Mie University, 1515 Uehama-cho, Tsu, Mie 514-5807, Japan

■ Photochemical Synthesis of Spiro-β-Lactams

Masazumi Ikeda, Takamasa Uchino, Midori Yamano, Hiroyuki Ishibashi, Yasumitsu Tamura, and Masaru Kido

*Kyoto Pharmaceutical University, Misasagi-Shichonocho, Yamashina, Kyoto 607-8414, Japan

■ Ring-transformation Reactions of Azaheteromodified Adamantanes and Related Derivatives

Koji Asai, Shoji Eguchi, and Tadashi Sasaki

*Faculty of Engineering, Nagoya University, Chikusa, Nagoya, Aichi 464-8601, Japan

■ [3+2]Cycloaddition Utilizing the Charactaristics of Organic Silicon Compounds — Study on Regio- and Stereoselectivity of Pyrrolidine Ring Formation

Nobuyuki Imai, Hiromi Kotaki, Yoshiyasu Terao, and Kazuo Achiwa

*Schol of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan

■ Stereoselective Synthesis of Pyrrolidines by Intramolecular Haloamidation

Yoshinao Tamaru, Shinichi Kawamura, Kunitada Tanaka, and Zenichi Yoshida

*Faculty of Engineering, Kyoto University, Yoshida, Sakyou-ku, Kyoto 606-8501, Japan

■ Synthesis of Heterocycles via Vinyl Cations

Tsugio Kitamura, Shinjiro Kobayashi, and Hiroshi Taniguchi

*Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan

■ Syntheses of Diazepines from Pyridine Azides

Hiroyuki Sawanishi, Kayoko Tajima, Makoto Osada, and Takashi Tsuchiya

*School of Pharmacy, Hokuriku University, 3-Ho, Kanagawa machi, Kanazawa 920-1181, Japan

■ The Reactions of Nitrene for the Conjugated π-Systems

Kyosuke Satake, Hiroshi Mizushima, Masaru Kimura, and Shiro Morosawa

*Department of Chemistry, Faculty of Science, Okayama University, 3-1-1 Tsushima-naka, Okayama 700-8530, Japan

■ Stereochemical Aspects of 1,3-Dipolar Cycloaddition Reactions of Heterocyclic N-Ylides to Olefinic Dipolarophiles

Otohiko Tsuge, Shuji Kanemasa, and Shigeori Takenaka

*Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan

■ Synthesis of Aziridine Derivative from α-Silyl Carbanion and Their Mutagenicity

Takeo Konakahara, Masayuki Matsuki, Kenji Sato, Yoshiharu Hisamatsu, and Hidetsuru Matsushita

*Department of Industrial Chemistry, Faculty of Science and Technology, Science University of Tokyo, 2641 Yamazaki, Noda, Chiba 278-8510, Japan

■ Synthesis of Tricyclic Compounds Using 2(1H)-Quinoxalinone Derivatives

Kenji Makino, Gozyo Sakata, Katsushi Morimoto, and Yoshinori Ochiai

*Central Research Institute, Nissan Chemical Industries Ltd., 722-1 Tsuboicho, Funabashi, Chiba 274-8507, Japan

■ Synthesis of Novel Quinoxalinyl-1,5-benzodiazepines by Ring Transformation

Yoshihisa Kurasawa and Atsushi Takada

*School of Pharmaceutical Sciences, Kitasato University, Kitasato University