CVM Cardiovascular Medicine 1664-204X 1664-2031 EMH Schweizerischer Ärzteverlag AG Farnsburgerstrasse 8 CH-4132 Muttenz 02152 Case report Hypertension Monitoring the personalized effects of antihypertensive drugs using the Aktiia optical device: a 4-month follow-up Sola Josep Aktiia SA, Neuchâtel Fallet Sibylle Aktiia SA, Neuchâtel Wuerzner Gregoire gregoire.wuerzner@chuv.ch SWITZERLAND 01 03 2022 25 02 0 0 Copyright: EMH Schweizerischer Ärzteverlag AG 2022 EMH Schweizerischer Ärzteverlag AG "Cardiovascular Medicine" is an open access publication of EMH published in accordance with the terms of the Creative Commons licence attribution - NonCommercial - NoDerivatives 4.0 International. You are free to share, copy and redistribute the material in any medium or format under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. NonCommercial — You may not use the material for commercial purposes. NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material. "Non-commercial" means not primarily intended for or directed towards commercial advantage or monetary compensation. The incorporation of publications in commercial products, the use of publications to advertise for commercial products or services and any other usage that directly or indirectly pursues commercial interests is subject to the express previous consent of the publishing house as part of a written agreement. Please send us your request in writing. Exact indication of the publication from which you would like to reproduce material and detailed information about its intended use help to facilitate and expedite request processing.

The reduction of blood pressure (BP) is associated with a significant reduction of cardiovascular events and all-cause mortality. After lifestyle interventions, antihypertensive drugs are routinely administrated to lower BP. The optimization of antihypertensive therapies requires the identification of the best-adapted drugs for each patient, followed by the titration of doses or by the combination of drugs. Automated cuffless BP monitoring devices based on optical sensors have the potential to provide new insights in the daily monitoring of the effectiveness of antihypertensive therapies over weeks. This case report illustrates the use of the CE-marked Aktiia Bracelet optical device for the monitoring of a 39 year-old male hypertensive patient for four months during which two drug therapies were tested.