CVM Cardiovascular Medicine 1664-204X 1664-2031 EMH Schweizerischer Ärzteverlag AG Farnsburgerstrasse 8 CH-4132 Muttenz 02234 10.4414/cvm.2022.02234 Review article Heart failure Extracorporeal Life Support Use in Cardiac and Circulatory Failure: A Summary of Recently Published S3 Guidelines Dzemali Omer omer.dzemali@triemli.zuerich.ch Municipal Hospital Triemli: Stadtspital Triemli | Zurich | SWITZERLAND Starck Christoph Wessel Lukas Miera Oliver Werdan Karl Burckhardt Marion Muellenbach Ralf Jaksties Rolf Schmidt Florian Wiebe Karsten Schmid Christof Kluge Stefan Pilarczyk Kevin Haake Nils Schaible Thomas Flemmer Andreas Klotz Stefan Assmann Alexander Janssens Uwe Lubnow Matthias Herber-Jonat Susanne Ferrari Markus Buchwald Dirk Ensminger Stephan Zausig York Beckmann Andreas Rosenberg Mark Kelm Malte Hennersdorf Marcus Hartog Christiane Fischer Stefan Rastan Ardawan Zimpfer Daniel Fründ Andreas Maier Sven Ruttmann-Ulmer Elfriede Groesdonk Heinrich Schlensak Christian Nothacker Monika Buerke Michael Köditz Harald Michels Guido Krüger Lars Boeken Udo 01 11 2022 25 06 0 0 Copyright: EMH Schweizerischer Ärzteverlag AG 2022 EMH Schweizerischer Ärzteverlag AG "Cardiovascular Medicine" is an open access publication of EMH published in accordance with the terms of the Creative Commons licence attribution - NonCommercial - NoDerivatives 4.0 International. You are free to share, copy and redistribute the material in any medium or format under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. NonCommercial — You may not use the material for commercial purposes. NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material. "Non-commercial" means not primarily intended for or directed towards commercial advantage or monetary compensation. The incorporation of publications in commercial products, the use of publications to advertise for commercial products or services and any other usage that directly or indirectly pursues commercial interests is subject to the express previous consent of the publishing house as part of a written agreement. Please send us your request in writing. Exact indication of the publication from which you would like to reproduce material and detailed information about its intended use help to facilitate and expedite request processing.

Extracorporeal Life-Support (ECLS) represents a widely accepted treatment modality for patients with cardiac and/or respiratory failure failing to respond to conventional medical therapy. Through the establishment of a modified cardiopulmonary bypass circuit, ECLS provides a mechanism for temporary cardiac support and gas exchange allowing patients to recover from existing life-threatening cardiac and/or lung disease. This article summarizes the current recommendations for ECLS therapy in adults, which are based on the recently published S3 guidelines entitled "Extracorporeal circulation (ECLS / extracorporeal membrane oxygenation = ECMO), use in cardiac and circulatory failure".