SANP Swiss Archives of Neurology, Psychiatry and Psychotherapy 2297-7007 2297-6981 EMH Schweizerischer Ärzteverlag AG Farnsburgerstrasse 8 CH-4132 Muttenz 03140 10.4414/sanp.2020.03140 Review article Schizophrenia, schizotypal and delusional disorders Psychodynamic psychiatry and neurobiology Boeker Heinz boeker@bli.uzh.ch Zurich | SWITZERLAND 02 10 2020 171 05 0 0 Copyright: EMH Schweizerischer Ärzteverlag AG 2020 EMH Schweizerischer Ärzteverlag AG "Swiss Archives of Neurology, Psychiatry and Psychotherapy" is an open access publication of EMH published in accordance with the terms of the Creative Commons licence attribution - NonCommercial - NoDerivatives 4.0 International. You are free to share, copy and redistribute the material in any medium or format under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. NonCommercial — You may not use the material for commercial purposes. NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material. "Non-commercial" means not primarily intended for or directed towards commercial advantage or monetary compensation. The incorporation of publications in commercial products, the use of publications to advertise for commercial products or services and any other usage that directly or indirectly pursues commercial interests is subject to the express previous consent of the publishing house as part of a written agreement. Please send us your request in writing. Exact indication of the publication from which you would like to reproduce material and detailed information about its intended use help to facilitate and expedite request processing. <p>This paper focuses on the relationship between Psychodynamic Psychiatry and Neurobiology, especially on the question whether and how Neurobiology may contribute to the development of Psychodynamic Psychiatry. Mental functions such as the self, the conscious and the unconscious, and the psychological  and neuronal mechanisms and functions underlying these are focussed on [2]. The self in psychiatric patients is considered in a relational perspective... First, the historical development of Psychodynamic Psychiatry is addressed and its core principles are re-considered in the perspective of actual research, especially neuroscientific research. Secondly, the threedimensional model of Neuropsychodynamic Psychiatry is described, which tries to connect the essentials of Psychodynamic Psychiatry and of the “First-Person-Neuroscience”. This model is applied to depression and schizophrenia as clinical examples which underline the practical relevance of the neuro-psychodynamic approach for psychiatric treatment and psychotherapy. Third, spatio-temporal psychopathology is hypothesized as a "current currency" between brain and mind.</p>