Since most of the early signs of psychological distress are nonspecific and often under the threshold of a diagnosable disorder, especially in early adolescence, a dimensional and transdiagnostic approach is needed to guide early interventions. In this review, we focus on the transdiagnostic mechanism of emotion dysregulation hypothesized to underlie a group of psychopathologies that we named “emotion dysregulation disorders”. Some promising interventions useful at different stages of the evolution of such disorders (from subclinical to clinical ones) are briefly presented. Among them, we propose Cognitive-Behavioral therapies, Mindfulness-Based Interventions, and Mentalization-Based Treatment. The MBIs are an essential part of our ongoing study on the effects of an 8-weeks regular practice of Mindfulness on non-clinical adolescents between 13 and 15 years old. We finally conclude with a proposition of a potential clinical staging model for emotion dysregulation disorders.