SMF Schweizerisches Medizin-Forum 1424-4020 1424-3784 EMH Schweizerischer Ärzteverlag AG Farnsburgerstrasse 8 CH-4132 Muttenz 08588 10.4414/smf.2021.08588 Der besondere Fall Labormedizin Nephrologie Ophthalmologie Oto-Rhino-Laryngologie Syndrome Urologie Das Alport-Syndrom und seine Verwandten Henoch Friederike friederike.henoch@googlemail.com Spital Zweisimmen, Spital STS AG | Karl Haueter Strasse | Zweisimmen | 3770 | SWITZERLAND Stauffer Anita Spital Zweisimmen, Spital STSAG von Gradowski Markus Spital Zweisimmen, Spital STSAG 02 03 2021 21 0910 168 170 Copyright: EMH Schweizerischer Ärzteverlag AG 2021 EMH Schweizerischer Ärzteverlag AG "Swiss Medical Forum" is an open access publication of EMH published in accordance with the terms of the Creative Commons licence attribution - NonCommercial - NoDerivatives 4.0 International. You are free to share, copy and redistribute the material in any medium or format under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. NonCommercial — You may not use the material for commercial purposes. NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material. "Non-commercial" means not primarily intended for or directed towards commercial advantage or monetary compensation. The incorporation of publications in commercial products, the use of publications to advertise for commercial products or services and any other usage that directly or indirectly pursues commercial interests is subject to the express previous consent of the publishing house as part of a written agreement. Please send us your request in writing. Exact indication of the publication from which you would like to reproduce material and detailed information about its intended use help to facilitate and expedite request processing.

Das Alport Syndrom beinhaltet neu jegliche Erkrankung, die mit einer Mutation im Kollagen Typ IV α3, α4 oder α5 einhergeht. Diese können verschiedene Ausprägungen haben. Es sollten regelmässige Nachkontrollen erfolgen, um im Bedarfsfall prophylaktische Massnahmen frühzeitig zu beginnen. Eine genetische Analyse zur genauen Klassifikation bei Kollagen IV Erkrankungen ist notwendig. Die Diagnose einer dünnen Basalmembran ist eine histomorphologische.