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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">SMF</journal-id>
      <journal-title-group>
        <journal-title>Schweizerisches Medizin-Forum</journal-title>
      </journal-title-group>
      <issn pub-type="epub">1424-4020</issn>
      <issn pub-type="ppub">1424-3784</issn>
      <publisher>
        <publisher-name>EMH Schweizerischer Ärzteverlag AG</publisher-name>
        <publisher-loc>Farnsburgerstrasse 8
CH-4132 Muttenz</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">09113</article-id>
      <article-id pub-id-type="doi">10.4414/smf.2023.09113</article-id>
      <article-categories>
        <!-- rubric -->
        <subj-group subj-group-type="Article Type">
          <subject>Der besondere Fall</subject>
        </subj-group>
        <!-- topics -->
        <subj-group subj-group-type="Classification">
          <subject>Allergologie / Immunologie</subject>
          <subject>Dermatologie und Venerologie</subject>
          <subject>Intensivmedizin</subject>
          <subject>Klinische Pharmakologie und Toxikologie</subject>
          <subject>Nephrologie</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Akute Niereninsuffizienz als seltene Komplikation nach multiplen Bienenstichen</article-title>
      </title-group>
      <contrib-group>
        <contrib id="author-1" contrib-type="author" corresp="yes">
          <contrib-id contrib-id-type="orcid"/>
          <name>
            <surname>Hofer</surname>
            <given-names>Isabel  M.</given-names>
          </name>
          <email>isa.hofer@sro.ch</email>
          <aff>SRO Spital Langenthal | St. Urbanstrasse 67 | Langenthal | 4900 | SWITZERLAND</aff>
        </contrib>
        <contrib id="author-2" contrib-type="author" corresp="no">
          <contrib-id contrib-id-type="orcid"/>
          <name>
            <surname>Künzi</surname>
            <given-names>Thomas</given-names>
          </name>
          <email/>
          <aff>SRO Spital Langenthal</aff>
        </contrib>
        <contrib id="author-3" contrib-type="author" corresp="no">
          <contrib-id contrib-id-type="orcid"/>
          <name>
            <surname>Marti</surname>
            <given-names>Grischa</given-names>
          </name>
          <email/>
          <aff>SRO Spital Langenthal</aff>
        </contrib>
      </contrib-group>
      <pub-date pub-type="epub" date-type="pub" iso-8601-date="2023.06.14">
        <day>14</day>
        <month>06</month>
        <year>2023</year>
      </pub-date>
      <volume>23</volume>
      <issue>24</issue>
      <fpage>1131</fpage>
      <lpage>1133</lpage>
      <permissions>
        <copyright-statement>Copyright: EMH Schweizerischer Ärzteverlag AG</copyright-statement>
        <copyright-year>2023</copyright-year>
        <copyright-holder>EMH Schweizerischer Ärzteverlag AG</copyright-holder>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by-nc-nd/4.0/">
          <license-p>"Swiss Medical Forum" is an open access publication of EMH published in accordance with the terms of the Creative Commons licence attribution - NonCommercial - NoDerivatives 4.0 International. You are free to share, copy and redistribute the material in any medium or format under the following terms:</license-p>
          <license-p>Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.</license-p>
          <license-p>NonCommercial — You may not use the material for commercial purposes.</license-p>
          <license-p>NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.</license-p>
          <license-p>"Non-commercial" means not primarily intended for or directed towards commercial advantage or monetary compensation. The incorporation of publications in commercial products, the use of publications to advertise for commercial products or services and any other usage that directly or indirectly pursues commercial interests is subject to the express previous consent of the publishing house as part of a written agreement.</license-p>
          <license-p>Please send us your request in writing. Exact indication of the publication from which you would like to reproduce material and detailed information about its intended use help to facilitate and expedite request processing.</license-p>
        </license>
      </permissions>
      <abstract abstract-type="article" xml:lang="de">
        <p>Hintergrund: Jährlich werden der SUVA etwa 20.000 Schadensfälle durch Insektenstiche gemeldet. Die Hälfte entfällt hierbei auf Zeckenstiche. Wespen verursachen 3000, Bienen 2300 Meldungen. Vor allem ab Juli/August werden die Insekten aktiv. Bei Hymenopterenstichen werden normale und schwere Lokalreaktionen von systemisch-allergischen, sowie systemisch-toxischen Reaktionen unterschieden. Diese systemisch-toxischen Reaktionen umfassen neben Rhabdomyolyse, disseminierter intravasaler Gerinnung, intravaskulärer Gerinnung, auch akutes Leber- und Nierenversagen und sind meist direkte Folge des Hymenopterengiftes (4). Nach multiplen Bienenstichen (in der Regel 50 bis mehrere hundert) kann es in Folge einer toxischen Reaktion zu Multiorganversagen und sogar Tod kommen. Etwa 20 Stiche/kg Körpergewicht werden als potenziell tödlich angesehen (2), was bei kleinen Kindern schon weniger als 50 Stichen entsprechen kann.   In diesem Beitrag stellen wir einen Patienten vor, der bei über 1500 Bienenstichen Toxin-induzierte Symptome entwickelte.</p>
      </abstract>
    </article-meta>
  </front>
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