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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">SMF</journal-id>
      <journal-title-group>
        <journal-title>Schweizerisches Medizin-Forum</journal-title>
      </journal-title-group>
      <issn pub-type="epub">1424-4020</issn>
      <issn pub-type="ppub">1424-3784</issn>
      <publisher>
        <publisher-name>EMH Schweizerischer Ärzteverlag AG</publisher-name>
        <publisher-loc>Farnsburgerstrasse 8
CH-4132 Muttenz</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">09277</article-id>
      <article-id pub-id-type="doi">10.4414/smf.2023.09277</article-id>
      <article-categories>
        <!-- rubric -->
        <subj-group subj-group-type="Article Type">
          <subject>Der besondere Fall</subject>
        </subj-group>
        <!-- topics -->
        <subj-group subj-group-type="Classification">
          <subject>Endokrinologie / Diabetologie und Stoffwechsel </subject>
          <subject>Kardiologie</subject>
          <subject>Kinder- und Jugendmedizin</subject>
          <subject>Klinische Pharmakologie und Toxikologie</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Akute Levothyroxin-Intoxikation bei Kindern </article-title>
      </title-group>
      <contrib-group>
        <contrib id="author-1" contrib-type="author" corresp="yes">
          <contrib-id contrib-id-type="orcid"/>
          <name>
            <surname>Laesser</surname>
            <given-names>Céline  Isabelle</given-names>
          </name>
          <email>celaesser@gmail.com</email>
          <aff>Assistenzärztin | Kinderspital, Pädiatrische Endokrinologie-Diabetologie | Kantonsspital Aarau AG | Tellstrasse 25 | Aarau | 5001 | SWITZERLAND</aff>
        </contrib>
        <contrib id="author-2" contrib-type="author" corresp="no">
          <contrib-id contrib-id-type="orcid"/>
          <name>
            <surname>Kuhlmann</surname>
            <given-names>Beatrice</given-names>
          </name>
          <email/>
          <aff>Kinderspital, Pädiatrische Endokrinologie-Diabetologie | SWITZERLAND</aff>
        </contrib>
        <contrib id="author-3" contrib-type="author" corresp="no">
          <contrib-id contrib-id-type="orcid"/>
          <name>
            <surname>Szinnai</surname>
            <given-names>Gabor</given-names>
          </name>
          <email/>
          <aff>Pädiatrische Endokrinologie-Diabetologie | SWITZERLAND</aff>
        </contrib>
        <contrib id="author-4" contrib-type="author" corresp="no">
          <contrib-id contrib-id-type="orcid"/>
          <name>
            <surname>Bieri</surname>
            <given-names>Andreas</given-names>
          </name>
          <email/>
          <aff>Kinderspital, Pädiatrische Endokrinologie-Diabetologie | SWITZERLAND</aff>
        </contrib>
      </contrib-group>
      <pub-date pub-type="epub" date-type="pub" iso-8601-date="2023.09.27">
        <day>27</day>
        <month>09</month>
        <year>2023</year>
      </pub-date>
      <volume>23</volume>
      <issue>39</issue>
      <fpage>1334</fpage>
      <lpage>1336</lpage>
      <permissions>
        <copyright-statement>Copyright: EMH Schweizerischer Ärzteverlag AG</copyright-statement>
        <copyright-year>2023</copyright-year>
        <copyright-holder>EMH Schweizerischer Ärzteverlag AG</copyright-holder>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by-nc-nd/4.0/">
          <license-p>"Swiss Medical Forum" is an open access publication of EMH published in accordance with the terms of the Creative Commons licence attribution - NonCommercial - NoDerivatives 4.0 International. You are free to share, copy and redistribute the material in any medium or format under the following terms:</license-p>
          <license-p>Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.</license-p>
          <license-p>NonCommercial — You may not use the material for commercial purposes.</license-p>
          <license-p>NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.</license-p>
          <license-p>"Non-commercial" means not primarily intended for or directed towards commercial advantage or monetary compensation. The incorporation of publications in commercial products, the use of publications to advertise for commercial products or services and any other usage that directly or indirectly pursues commercial interests is subject to the express previous consent of the publishing house as part of a written agreement.</license-p>
          <license-p>Please send us your request in writing. Exact indication of the publication from which you would like to reproduce material and detailed information about its intended use help to facilitate and expedite request processing.</license-p>
        </license>
      </permissions>
      <abstract abstract-type="article" xml:lang="de">
        <p>Intoxikationen mit Schilddrüsenhormonpräparaten kommen bei Kindern und Jugendlichen häufig vor  .  In diesem Case Report wird der Fall zweier Geschwister beschrieben, die sich gemeinsam nach Einnahme hoher Dosen LT4 präsentierten und einen komplikationslosen Verlauf zeigten. Mögliche Symptome einer Intoxikation mit Levothyroxin (LT4) umfassen Tachykardie, Fieber, Diarrhoe, Hyperaktivität, Agitation, Tremor, Hyperhidrose, abdominelle Schmerzen und Hypertension. Die Symptomatik tritt oft zeitlich verzögert auf. Selten beschrieben sind zudem Krampfereignisse oder thyreotoxische Krisen. Bei Kindern verlaufen die meisten Fälle harmlos.</p>
      </abstract>
    </article-meta>
  </front>
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